![]() ![]() Symptoms lasting no more than 24 hours and generally shorter.More symptoms and history that may help diagnose transient global amnesia: No signs of damage to a particular area of the brain, such as being unable to move an arm or leg, movements you can't control, or problems understanding words.Normal cognition, such as the ability to recognize and name familiar objects and follow simple directions.Being awake and alert and knowing who you are, despite memory loss.Sudden onset of confusion that includes memory loss, seen by a witness.You must have these signs and symptoms to be diagnosed with transient global amnesia: Once that symptom is confirmed, ruling out other possible causes of amnesia is important. The main symptom of transient global amnesia is being unable to create new memories and remember the recent past. Transient global amnesia isn't serious, but it can still be frightening. During recovery, you may begin to remember events and circumstances. Episodes of transient global amnesia always get better slowly over a few hours. With transient global amnesia, you do remember who you are, and you recognize the people you know well. The condition most often affects people in middle or older age. ![]() You may also draw a blank when asked to remember things that happened a day, a month or even a year ago. You may keep repeating the same questions because you don't remember the answers you've just been given. You may not remember anything about what's happening right now. You can't remember where you are or how you got there. This confused state isn't caused by a more common neurological condition, such as epilepsy or stroke.ĭuring an episode of transient global amnesia, a person is unable to create new memory, so the memory of recent events disappears. EEG demonstration of seizures may be difficult and the response to antiepileptic drugs effective on partial seizures is usually good.Transient global amnesia is an episode of confusion that comes on suddenly in a person who is otherwise alert. The red flag supportive of an epileptic origin is the repetition of stereotyped amnesic episodes. Partial seizures, most often mesio-temporal, more rarely frontal, may be the cause of transient amnesia in the elderly, in the absence of a past history of epilepsy. It results from lesions involving various mechanisms and locations, mainly subcortical. A vascular origin must be considered when amnesia is accompanied by other neurological symptoms, and when the regression of the amnesic disorder is slow, lasting several days. The latter are more often due to a hypersensitivity to anticholinergic drugs, in particular in patients presenting with a covert, incipient Alzheimer's disease. The former may occur in a non-anxious subject, who is not a usual consumer of BZ and takes a single dose. Iatrogenic amnesias are mainly caused by benzodiazepines (BZs) or anticholinergics. It may be the consequence of a spreading depression similar to that described in migraine with aura, but other arguments support an ischemic mechanism. ![]() The mechanism of TGA remains a matter of discussion. It occurs more often after age 50, with no identified cause, even if some authors accept emotional stress or minor head trauma as occasional precipitants. TGA is the prototypical picture of transient amnesia. According to the literature, transient psychogenic amnesia, which is a frequent cause of amnesia at age 30 to 50, is very rare in the elderly. Vascular and epileptic amnesia are less common. The two main aetiologies of transient amnesia in the elderly are idiopathic transient global amnesia (TGA) and iatrogenic or toxic amnesia. ![]()
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